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SAT0534 Early Inflammatory Arthritis Detection using a Self-Administered Tool in a Canadian Francophone Population
  1. R. Tavares1,
  2. P. L. Veinot2,
  3. M. Zummer3,
  4. A. Zhao4,
  5. M. J. Bell2,4
  1. 1UNCOVER Clinical Research Company, Milton
  2. 2Division of Rheumatology, Sunnybrook Health Sciences Centre, Toronto
  3. 3Service de Rhumatologie, Centre Hospitalier Maisonneuve-Rosemont, Montreal
  4. 4Department of Medicine, University of Toronto, Toronto, Canada

Abstract

Background A self-administered Early Inflammatory Arthritis (EIA) tool has been developed.1-3

Objectives The purpose of this study is to cross-culturally adapt the developed EIA detection tool for the Canadian Francophone population and to determine its psychometric and discriminative properties. The external validity of a scoring algorithm previously developed in an English-speaking population was tested.

Methods Three groups were recruited from outpatient clinics at two tertiary care hospitals: 92 EIA; 106 established IA; 94 non-IA. The current study was completed in four phases. Phase I: Translation and adaptation of the English tool into Canadian Francophone culture was conducted independently by two sets of translators. Phase II: A committee adjudicated the translated and adapted items to derive a single cross-culturally adapted tool. Phase III: A pilot validation study of the tool was conducted on a Canadian Francophone sample of 80 participants. Comprehensibility, internal consistency and test-retest reliability of the tool were determined. Phase IV: A full-scale validation study of 292 Canadian Francophone participants was conducted to determine the discriminative properties of the tool.

Results A translated and cross-culturally adapted to Canadian French version of the EIA Detection Tool, with 100% committee agreement was produced. Comprehensibility approached unity for all tool items. The internal consistency Kuder-Richardson-20 was 0.96 (p<0.0001). The mean test-retest reliability kappa (standard error, SE) was 0.67 (0.03). The intraclass correlation coefficient (ICC) for summed ‘yes’ responses between test and retest phases was 0.77 (p<0.0001) and for algorithm scores was 0.86 (p<0.0001). The scoring algorithm receiver operating characteristic plot area under the curve (SE) was 0.818 (0.002).

Conclusions The tool has favorable measurement and discriminative properties. A cross-culturally adapted and validated EIA Detection Tool for Canadian Francophones may improve appropriate care for this population.

References

  1. Bell MJ, et al. BMC Musculoskelet Disord 2010;11:50.

  2. Tavares R, et al. J Rheumatol 2013 (in press).

  3. Tavares R, et al. Rheumatology 2013 (submitted).

References

Acknowledgements This study was financial supported by a Canadian Arthritis Network Discovery Advancement Program peer-reviewed grant. We thank the following individuals for their contributions: bilingual translators, linguist (Rose Gorrie), methodologist (Dr. Lucie Brosseau), primary care practitioner (Dr. Diane Giroux), lay persons and moderator/coordinator (Isabelle Provost) who contributed to the translation of the tool; on-site staff who assisted with data collection (Diane Ferland, Isabelle Gagnon, Chantal Jaques, Evelyne Lejeune, Ann Ranking, Francine Raymond, Michelle Roy); and participating rheumatologists - Dr. Louis Bessette, Groupe de recherche en maladie osseueses (GRMO) Inc.; Dr. Gilles Boire, Centre de Recherche Clinique - Centre Hospitalier Universitaire de Sherbrooke; Dr. Isabelle Fortin, Centre de santé et de services sociaux de Rimouski-Neigette; Dr. Mark Hazeltine, Centre de rhumatologie de Laval; Dr Leo Picard, Centre Hospitalier Hopital Georges-L. Dumont Régie Vitalité; Dr. Jean-Luc Tremblay, Centre de Recherche Musculosquelettique.

Disclosure of Interest None Declared

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