Background Obesity has been associated with higher levels of fibromyalgia symptoms and worse quality of life.
Objectives To evaluate the prevalence of obesity and its correlates in a well characterized fibromyalgia cohort.
Methods All new consecutive patients clinically diagnosed with fibromyalgia between September 1st, 2008 and January 31st, 2011, were enrolled in the study.
Three hundred and six patients were enrolled. We recorded detailed demographics, symptoms, family history and comorbidities. All patients completed the Brief Patient Health Questionnaire (PHQ -9), Epworth Sleepiness Scale (ESS), Mood Disorders Questionnaire (MDQ), Fibromyalgia impact questionnaire (FIQ), Symptom Intensity Scale (SIS) and Health Assessment Questionnaire Disability Index (HAQ-DI).
Results Of the 306 fibromyalgia patients, 34.2% were overweight and 43.3% were obese. The strongest BMI correlations were found with: with prior history of sleep apnea r=0.367 (0.222, 0.512), p=0.001; performing aerobic exercise 3 times a week for at least 30 minutes r=-0.250 (-0.401, -0.099), p=0.001; total number of medications taken for fibromyalgia r=0.336 (0.192, 0.466), p=0.001; total number of comorbidities r=0.246 (0.097, 0.385), p=0.001; MDQ score r=0.166 (0.013, 0.311), p =0.001; family history of bipolar disorder r=0.184 (0.031, 0.337), p=0.019; HAQ-DI r=0.231 (0.076, 0.385), p=0.004; the presence ³11 tender points r=-0.206 (-0.358, -0.054), p=0.008; depression score (PHQ-9) r=0.197 (0.045, 0.340), p =0.011; antidepressant use r=0.199 (0.048, 0.351), p=0.01; use of gabapentin or pregabalin r=0.176 (0.023, 0.328), p=0.024; use of narcotics r=0.172 (0.019, 0.324), p=0.028; use of sleep medications r=0.176 (0.023, 0.328), p=0.024.
Conclusions More than three quarters of all the 306 patients with fibromyalgia were overweight or obese. Obesity is associated with the lack of exercise, the number of comorbidities, associated mood disorders. The relationship of BMI with HAQ-DI and tender points suggests that weight is related to the severity of fibromyalgia and disability.
Disclosure of Interest None Declared