Background Frequency of psychiatric disorders in BD is a debated issue: while some experts attribute their presence to the chronicity of the illness, others think that they may be imputable to disease activity or to intrinsic features of the disease.
Objectives The primary aims were to determine the frequency of psychiatric disorders in BD patients, both with neurological involvement or without; the secondary aims were: to investigate a possible association between disease activity/organ involvement and psychiatric profile of the BD patients and to compare the distribution of psychiatric disorders of patients with BD with those in patients with other chronic diseases.
Methods One hundred and seven BD patients with a diagnosis of BD according the ISG criteria were studied. Demographic profile of the cohort studied are summarised in Table 1. Psychiatric disorders evaluated were: bipolar disorder, obsessive-compulsive disorder, depression and sleep disorder. Age and sex matched disease controls of systemic lupus erythematosus (SLE) and chronic arterial hypertension were included.
Results Prevalence of psychiatric disorders are shown in Table 2. No correlations were found between the presence of psychiatric disorders and disease activity/organ involvement. Moreover, the frequency of bipolar disorder resulted significantly higher than in disease controls (p < 0.001).
Conclusions Our results show a high frequency of psychiatric disorders in BD patients. This elevated prevalence both in BD patient with or without neurological involvement, in presence or absence of disease activity and in a higher frequency than in disease controls, strongly suggest that BD patients are characterised by a specific psychiatric profile.
Disclosure of Interest None Declared
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