Background Pain and functional limitation are the main reasons for patients undergoing total hip arthroplasty
Objectives To assess whether patient-reported outcomes (PROs) differ by underlying diagnosis in patients undergoing primary total hip arthroplasty (THA).
Methods We used the prospectively collected data from the Mayo Clinic Total Joint Registry to assess the association of diagnosis with index knee functional improvement, moderate-severe pain and moderate-severe activity limitation at 2- and 5-year follow-up after primary THA using multivariable-adjusted logistic regression analyses. Odds ratios (OR) and 95% confidence intervals (CI) are presented.
Results There were 7,139 primary THAs at 2-years and 4,234 at 5-years. In multivariable-adjusted analyses, at 2-year follow-up, compared to RA/inflammatory arthritis, OA were significantly associated with odds ratio (OR) [95% confidence interval (CI)] of moderate-severe activity limitation with OR 0.5 [95% CI: 0.3, 0.8] (p=0.01) at 2-years, but not at 5-years, OR of 0.7 (95% CI, 0.4, 1.4). There was no significant association of diagnosis with pain at 2- or 5-years. A diagnosis of avascular necrosis of bone (AVN) was associated with higher odds of moderate-severe pain with OR of 2.8 (95% CI, 0.9, 8.5; p=0.06) and 4.1 [95% CI: 1.2, 14.1] (p=0.02) at 5-years. No significant association of AVN with moderate-severe ADL limitation was noted at 2- or 5-years.
Conclusions We found that patients with OA had better ADL outcomes compared to patients with RA/inflammatory arthritis, but similar pain outcomes after primary THA. AVN is associated with worse pain outcomes, but similar ADL outcomes compared to RA/inflammatory arthritis after primary THA. Insights into mediators of these relationships need to be investigated to understand how xxx influences outcomes after TKA.
Disclosure of Interest None Declared