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Diagnosing Erdheim–Chester disease
  1. Giulio Cavalli,
  2. Alvise Berti,
  3. Corrado Campochiaro,
  4. Lorenzo Dagna
  1. Unit of Medicine and Clinical Immunology, Vita-Salute San Raffaele University and San Raffaele Scientific Institute, Milan, Italy
  1. Correspondence to Professor Lorenzo Dagna, Unit of Medicine and Clinical Immunology, Vita-Salute San Raffaele University and San Raffaele Scientific Institute, Via Olgettina 60, Milan 20132, Italy; lorenzo.dagna{at}unisr.it

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Although we generally agree with Juanos-Iborra et al1 who noted that some of the most common manifestations of Erdheim–Chester disease (ECD) at time of onset (such as skeletal, constitutional or even neurological symptoms) may lack adequate specificity for a timely and prompt diagnosis, it is conceivable that the same manifestations, if unexplained, may often lead to …

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