Background To the best of our knowledge, no previous reports have addressed concomitantly quantitative and semi-quantitative sonographic measurements obtained from several peripheral joints of healthy people, and compared them among different age groups.
Objectives To describe quantitative and semi-quantitative ultrasound measurements in healthy joints and compare them among different age groups.
Methods Bilateral ultrasound measurement of small, medium and large joints were performed in 130 healthy adult volunteers, stratified into five age groups (A: 18-29, B: 30-39,C: 40-49, D: 50-59, E: 60-80 years), totalizing 46 joint recesses per patient. Sonographic measurements were correlated with age group and demographic variables: age, BMI, gender, skin color, smoking history and physical activity. My Lab 60 XVision machine (Esaote, Biomedica - Genova, Italy) with a linear probe (6-18 MHz) was used. Quantitative measurements of synovial recess (QSR) (mm) and semi-quantitative measures of synovial hypertrophy (SSH), Power Doppler (SPD) and bone erosion (SBE) (score 0-3), were performed. Articular cartilage (AC) at dorsal 2nd and 3rd metacarpophalangeal (MCP) were also evaluated (score 0-4).
Results 5,980 joint recesses were studied in 130 healthy adults; mean age 44.84, 76,9% women, 62,3% white. The mean (±SD) of QSR (mm) was: radiocarpal 2.0 (0.62); distal radioulnar 1.48 (0.37); ulnocarpal 1.39 (0.56); dorsal 2nd MCP 1.04 (0.54); palmar 2nd MCP 0.93 (0.66); dorsal 3rd MCP 0.81 (0.60); palmar 3rd MCP 0.83 (0.67); dorsal 2nd proximal interphalangeal joint of the hand (PIP) 0.47 (0.27); palmar 2nd PIP 0.85 (0.31); dorsal 3rd PIP 0.47 (0.35); palmar 3rd PIP 0.86 (0.35); coronoid fossa 1.07 (1.11); olecranean fossa 1.25 (1.16); glenohumeral (GH) axillary recess 2.46 (0.60); posterior GH recess 2.45 (0.52); hip 6.35 (1,25); knee 2.13 (1.47); talocrural (TC) 2.21 (1.09); talonavicular (TN) 2.61 (1.11); subtalar (ST) 2.16 (1.15), dorsal 1st metatarsophalangeal (MTP) joint 2.16 (0.83); dorsal 2nd MTP 2.32 (0.86); dorsal 5th MTP 0.73 (0.68). The largest QSR measurements (p<0.02) were observed in age groups D and E at the recesses: dorsal 2nd and 3rd PIP, dorsal 2nd and 3rd MCP, dorsal 5th MTP, palmar 2nd and 3rd MCP, olecranean fossa, TC and ST. The worst SSH scores (p<0.02) were observed at age groups D and E in the recesses: palmar 2nd and 3rd MCP, palmar 2nd and 3rd PIP, dorsal 2nd and 3rd PIP, dorsal 3rd MCP, 5th dorsal MTP, TN and ST. The worst SPD scores (p<0.016) were observed in age group E at the dorsal 3rd PIP and 3rd MCP. The worst SBE scores (p<0.041) were observed in age group E at the recesses: radiocarpal, ulnocarpal and posterior GH. Minor AC changes (score 1) (p<0.001) were observed in age groups D and E at the dorsal 2nd and 3rd MCP. There were few occasional correlations among ultrasound measurements and demographic variables. Inter-observer reliability (r) for the quantitative and semi-quantitative measurements ranged from 0.563 to 0.872 and 0.341 to 0.823, respectively.
Conclusions Articular sonographic measurements were performed in several types of joints in healthy adults at different age groups. The older age groups had the worst measurement scores.
K Ellegaard et al, 2007.
WA Schmidt et al, 2004.
Szkudlarek M et al, 2003.
DG Disler et al, 2000.
Disclosure of Interest None Declared