Objectives The aim of our study was to research eventual relationship betwen smoking, clinical activity and functional impairment in ankylosing spondylitis moroccan patients.

Methods In this cross sectional study 210 patients with back pain and limited movements, diagnosed with AS based on clinical, radiological, and laboratory examinations were included in this study. Patients were divided in 2 groups, 47 smokers and 163 none. The 2 groups were apparied for age and disease duration. Disease activity was evaluated with the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and functional impairment with the Bath Ankylosing Spondylitis Functional Index (BASFI). Analysis of association between and clinical activity and functional impairment was effected by T student.

Results

The mean of EVA pain, BASDAI, BASFI, ESR and C reactive protein was respectively 43±25.3, 4.6±2.7, 4.17±1.99, 10.2±12.4 and 20±19.75

In univariate analysis, there was no significant association between smoking and the activity or the functional impact of the disease respectively (p=0.4 and p=0.3).

Conclusions This study suggests that smoking status in AS moroccan patients seems to be not associated with clinical activity and functional impairment

Disclosure of Interest None Declared