Background Vitamin D insufficiency has emerged as a pandemic health issue in the recent times. Recent observations and hypotheses suggest that VDI may affect almost every system of the body. A number of observations have suggested an association between low serum levels of vitamin D and higher incidence of chronic pain .
Objectives The present study was, carried out to examine hypovitaminosis D and its determinants in female patients with myofascial pain syndrome.
Methods One hundred-sixty consecutive women with myofascial pain were included the study. For exclusion of patients with rickets and post menopausal osteoporosis, only the patients aged between 20-30 years were accepted to study. Patients with celiac disease, malabsorbtion symdrome, abnormal hepatic and renal function tests and patients taking medications known to affect vitamin D level were excluded. Informed consents were obtain from all patients. As part of their routine assessment, we recorded their vitamin D level (25-hydroxilated vitamin D), PTH, calsium, phosphor and other biocheimstry assays and pain characteristics with VAS. A risk factors list associated with hypovitaminosis like sun exposure (outfit), diet, pregnancy were applied. Logistic regression analysis were used in statistical evaluation with SPSS.
Results There is a significant correlation with vitamin D and visual analogue scale of pain. Logistic regression analysis were showed that outfit was a significant factor for low level vitamin D. Myofascial pain patients were divided into two groups, depending on their outfitting style. In group-1, plasma 25 (OH)2 vitamin D3 and body mass index (BMI) was statistically significantly lower (p<0.01). When the laboratory parameters were compared, There was no significant difference routine blood analyses. There were no difference between number of pregnancies and nutrition habbits between groups.
Conclusions There is no consensus on the even optimal levels of vitamin D. Vitamin D insufficiency constitutes an unrecognized epidemic in many populations worldwide. Therefore, the causal association of any disease with vitamin D insufficiency or deficiency should be judged cautiously. Vitamin D might help pain therapy in myofascial pain syndromes. But at least it must be examined.
Straube S, Andrew Moore R, Derry S, McQuay HJ (2009) Vitamin D and chronic pain. Pain 141(1–2):10–13
Disclosure of Interest None Declared