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AB1111 Disability in adult patients with idiopathic juvenile arthritis
  1. A.-M.-M. Ramazan1,
  2. M. Suta2
  1. 1Rheumatology Department, Emergency Clinical County Hospital
  2. 2Faculty of Medicine, Ovidius University, Constanta, Romania

Abstract

Background Juvenile Idiopathic Arthritis (JIA) is a inflammatory rheumatic disease of childhood that is reported with prevalence with large limits between 7 and 400/100 000 children. Although only a minority of patients with JIA have inflammatory disease as adult, functional involvement is significant. The prognosis was evaluated in many clinical trials through remission rate, functionality and radiological destruction on different groups, especially in children.

Objectives To assess disability in patients with persistent disease in a cohort of adult with JIA comparative with a group with rheumatoid arthritis from our district seen between May 2010 and Apr 2011.

Methods 21 patients with juvenile idiopathic arthritis, using ILAR criteria, were assessed. We had excluded the patients with juvenile ankylosing spondylitis. The outcome assessment included demographic, clinical status (disease activity, disability with HAQ score, damage assessment with JADI score), quality of life(SF-36) and inflammation tests (ESR,CRP). The control group with rheumatoid arthritis (26 patients) from our department were assessed on the same manner. The functional outcome were determined with linear regression.

Results The study patients had moderate disability with a mean of HAQ score 1.31±0.93 (95% CI=0.93-1.69). Through ANOVA test the results are similar with the group with rheumatoid arthritis (1.25±0.70). However we have noticed that 19% of study patients are no disability (p=0.06) in contrast with control patients. The HAQ score is influenced by pain (VAS, patient global assessment, tender joints), joint damage and by active disease. Therefore, the quality of life is decreased proportionally depending on disability and disease duration in contrast with control patient.

Conclusions Disability of adult patients with JIA after 21 years is moderate, but it is increasing proportionally with time and is most influencing by clinical factors.

Disclosure of Interest None Declared

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