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AB1009 Patients with rheumatic diseases are at risk of osteoporosis development
  1. L. Myasoutova,
  2. S. Lapshina,
  3. A. Vasilyev
  1. Kazan State Medical University, Kazan, Russian Federation

Abstract

Objectives Evaluation of changes in bone mineral density (BMD) in patients with rheumatic diseases.

Methods A retrospective analysis of protocols of X-ray densitometry was performed in patients who were at the dispensary observation in the Rheumatologic Centre of Kazan City in the period from January 2010 to January 2011. The changes of BMD in two points were taken into account: the lumbar spine and proximal femur. T-score was evaluated in postmenopausal women and men older than 50 years. Z-test was evaluated in women before menopause and men younger than 50 years. 347 patients were included in analysis. 231 of them had rheumatoid arthritis (RA), 63 – ankylosing spondylitis (AS) and 53 had osteoarthritis (OA).

Results 85 (24.5%) of 347 patients (74 women and 11 men) had osteoporosis and 143 (41.8%) patients (121 women and 21 men) had osteopenia according to the criteria of WHO. Distribution by rheumatic diseases was as follows. 55 (23.8%) of 231 patients with RA had osteoporosis and 89 (38.5%) – osteopenia. 13 (20.6%) of 63 patients with the AS had osteoporosis and 32 (50,8%) – osteopenia. Osteoporosis and osteopenia were revealed in 17 (32.1%) and 24 (45.3%) of 53 patients with OA, respectively.

Conclusions Osteoporosis is often met in rheumatic diseases, especially in RA and AS. However, the prevalence of osteopenia is even higher and this situation requires the actions for prevention of osteoporosis and fractures. In addition, osteoporosis and osteopenia in OA were observed much more often than it was thought previously.

Disclosure of Interest None Declared.

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