Background Disease activity has been evaluated in patients with PsA by using DAREA and another variables has been compared with DAREA.
Objectives The aim of this study is to find a reliable method for evaluating disease activity in patients with PsA.
Methods The study includes 50 patients which are diagnosed as PsA by using CASPAR (ClASification criteria for Psoriatic ARthitis) criteria. Each patient is examined substantially detailed. When necessary X-ray and magnetic resonance imaging are used. Erythrocyte sedimentation rate (ESR) and C reactive protein (CRP) values is recorded. For evaluating disease activity, DAS 28 (Disease Activity Score) and DAREA are used. HAQ (Health Assessment Questionnaire) is used for functional evaluation. Patient global assessment (PaGA), phsysican global assessment (PGA) and patient pain assessment (pain) are used in the study.
Results The dactylitis is %16, enthesis is %62 and nail involvement is %76 in the patients with PsA. We found that there is a significant correlation between DAREA and DAS 28, ESR, CRP, pain, PaGA, HAQ (p<0,05).
Conclusions PsA is an inflammatory arthritis that goes with dactylitis, enthesitis, spondylitis and peripheral arthritis that affects the daily activities and functions of a patient. Interest in PsA disease activitycriteria has increased with the treatment methods developed in recent years. DAREA is a disease activity criteria that was first developed for reactive arthritis. It’s calculated using five parameters which are: Sensitive joint count, swollen joint count, CRP, patient’s pain evaluation and global evaluation . Nell-Duxneuner et al. concluded that five parameters were needed to evaluate the disease activity in PsA. It can be seen that these five parameters are the same as DAREA’s parameters . Scholes et al. found that, DAREA is a sensitive criterion which correlates with the laboratory, radiological and clinical findings and argued that it can be used with the name of DAPSA (Disease Activity Index for Psoriatic Arthritis) . In our study DAREA correlates with laboratory findings (ESH and CRP), DAS 28, pain, PaGA and HAQ. It’s concluded that DAREA is a good measurement scale and practically and accurately reflects the disease activity in patients with PsA.
Eberl G, Studnicka-Benke A, Hitzelhammer H et al. Development of a Disease activity index fort he assessment of reactive arthritis (DAREA). Rheumatology 2000;39:148-155.
Nell-Duxneuner VP, Stamm TA, Machold KP et al. Evaluation of the appopriateness of composite disease activity measures for assessment of psoriatic arthritis Ann Rheum Dis 2010 69: 546-549
M Scholes, D Aletaha, J Funovits et al. Application of the DAREA/DAPSA score for assessment of the disease activity in psoriatic arthritis2010;69:1441-1447.
Disclosure of Interest None Declared
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.