Background Disturbance in sleep quality is important problem in ankylosing spondylitis(AS). Sleep problems may be affected from different aspects.
Objectives We aimed to investigate sleep quality and its association with the disease specific parameters, psychological status and quality of life in patients with AS.
Methods 80 AS patients (male/Female: 60/20) fullfilling modified New York criteria and 52 controls (M/F: 33/19), age and gender matched, were included into the study. Sleep quality was assessed using Pittsburg Sleep Quality Index (PSQI) in patients and controls. Pain was measured with visual analogue scale (VAS). Disease activity and functional status assesed by Bath AS Disease Activity Index (BASDAI) and Bath AS Functional Index (BASFI). Bath AS Metrology Index (BASMI) is used to evaluate mobility restrictions. Bath AS Radiology Index (BASRI) was used for evaluating the radiological damage. Psychological status and quality of life were assessed with the Hospital Anxiety-Depression Scale (HADS) and AS quality of life (ASQoL) measurements.
Results The patients with AS had significantly higher scores in subjective sleep quality, habitual sleep efficiency domains (p<0.001) and the total sore of the PSQI (p<0.05) compared to the healthy controls. Poor sleep quality (total PSQI score) was positively correlated with increased pain, poor quality of life, higher depressed mood, more active disease and restrictive mobility (p<0.01, p<0.01, p<0.01, p<0.01 and p<0.05, respectively). Also Pain was an independent contributor of poorer sleep quality (p=0.002).
Conclusions Sleep quality disturbed in AS. Pain, disease activity, depression, quality of life and increased mobility restriction have important impact on sleep quality.
Disclosure of Interest None Declared