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SLE, Sjögren’s and APS – clinical aspects (other than treatment)
AB0660 Prevalence of migraine in iraqi systemic lupus erythematosus patients
  1. F.I. Gorial1,
  2. A.M. Al-Mahdawi2,
  3. A. Shaker3
  1. 1Medicine-Rheumatology Unit, college of medicine
  2. 2Neurology, Al-Mustansiria college of Medicine
  3. 3Neurology, Baghdad Teacing Hospital, Baghdad, Iraq

Abstract

Background Systemic lupus erythematosus (SLE) is a relapsing-remitting autoimmune disease characterized by wide range of organ involvement and clinical symptoms (1). Headache is one of the common neurological findings in SLE (2). Migrainous headache is one of the most common neurological disorders and causes substantial levels of disability (3, 4).

Objectives To assess prevalence, type,severity, and predictors of migraine in Iraqi systemic lupus erythematosus (SLE) patients

Methods A case control study was conducted on patients attending Medical Department, Rheumatology unit& Neurological Department in Baghdad Teaching Hospital. Fifty patients with SLE diagnosed by rheumatologist according the American College of Rheumatology Revised criteria for the classification of systemic lupus erythematosus (5) were compared with 50 healthy control group matched for age and sex. The International Headache Society (IHS) classification (6) was used for diagnosis of migraine type.Migraine Disability Assessment (MIDAS) headache questionnaire was used to assess severity of migraine (7).

Results There were 15 (30%) migrainous subjects in SLE group compared with 6 (12%) migrainous subjects in the control group (P=0.027). In migrainous SLE patients, 80% have migraine without aura, 13.3% migraine with aura, and 6.7% retinal migraine. The moderately severe migraine was commonly observed (53.3%). There were significant associations between migraine and Raynaud’s phenomenon, neurosis, and anticardiolipin antibodies (p<0.05).

Conclusions There is high prevalence of migraine in Iraqi SLE patients. The common type and moderately severe migraine most commonly observed. Raynaud’s phenomenon, neurosis, and anticardiolipin antibodies are significant associates with migraine.

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  2. Lessa B, Santana A, Lima I, et al. Prevalence and classification of headache in patients with systemic lupus erythematosus. Clin Rheumatol 2006;25:850-3

  3. Andlin-Sobocki P, Jönsson B, Wittchen H U, and Olesen, J. Cost of disorders of the brain in Europe. Eur. J. Neurol. 2005; 12: 1–27.

  4. Wang SJ, Fuh JL, Young YH, Lu SR, and Shia B C. Prevalence of migraine in Taipei, Taiwan: a population-based survey. Cephalalgia 2000; 20: 566–72.

  5. Hochberg, MC. Updating the American College of Rheumatology Revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997; 40:1725.

  6. Headache Classification Subcommittee of the International Headache Society. The International Classification of Headache Disorders: 2nd edition. Cephalalgia 2004; 24 Suppl 1:9-160.

  7. Migraine Disability Assessment (MIDAS) headache questionnaire. (© Innovative Medical Research 1997.

Disclosure of Interest None Declared

https://doi.org/10.1136/annrheumdis-2012-eular.660

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