Background Systemic lupus erythematosus (SLE) is a relapsing-remitting autoimmune disease characterized by wide range of organ involvement and clinical symptoms (1). Headache is one of the common neurological findings in SLE (2). Migrainous headache is one of the most common neurological disorders and causes substantial levels of disability (3, 4).
Objectives To assess prevalence, type,severity, and predictors of migraine in Iraqi systemic lupus erythematosus (SLE) patients
Methods A case control study was conducted on patients attending Medical Department, Rheumatology unit& Neurological Department in Baghdad Teaching Hospital. Fifty patients with SLE diagnosed by rheumatologist according the American College of Rheumatology Revised criteria for the classification of systemic lupus erythematosus (5) were compared with 50 healthy control group matched for age and sex. The International Headache Society (IHS) classification (6) was used for diagnosis of migraine type.Migraine Disability Assessment (MIDAS) headache questionnaire was used to assess severity of migraine (7).
Results There were 15 (30%) migrainous subjects in SLE group compared with 6 (12%) migrainous subjects in the control group (P=0.027). In migrainous SLE patients, 80% have migraine without aura, 13.3% migraine with aura, and 6.7% retinal migraine. The moderately severe migraine was commonly observed (53.3%). There were significant associations between migraine and Raynaud’s phenomenon, neurosis, and anticardiolipin antibodies (p<0.05).
Conclusions There is high prevalence of migraine in Iraqi SLE patients. The common type and moderately severe migraine most commonly observed. Raynaud’s phenomenon, neurosis, and anticardiolipin antibodies are significant associates with migraine.
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Disclosure of Interest None Declared