Background Patients with knee osteoarthritis (KOA), due to age, walking functional impairment and/or a high prevalence of obesity, are at a high risk of metabolic disorders and cardiovascular (CV) comorbidities, especially in patients referred to rheumatologists or orthopedic surgeons because of advanced disease for symptom control or surgery.
Objectives To evaluate the frequency of metabolic disorders and CV comorbidity in patients with symptomatic KOA referred to a rheumatologist in a primary care setting.
Methods Consecutive patients aged >50 y referred period to a rheumatology practice in a primary care setting because of symptomatic KOA during a 12-month period. Diagnostics related to CV comorbidity and/or glycemic or lipid disorders (hypertension, diabetes, ischemic heart disease, heart failure, cerebrovascular disorder, venous insufficiency or dyslipemia) were obtained for each patient from the HC3 (Història Clínica Compartida de Catalunya), a computerized database from the public health service. Patients with soft tissue disorders (e.g. shoulder tendinitis, plantar fasciitis, etc) adjusted for age were used as control group. Patients with soft tissue disorders (e.g. shoulder tendinitis, plantar fasciitis, etc) adjusted for age were used as control group.
Results One hundred and eighty-four patients with KOA and 254 with soft tissue conditions were included in this cross-sectional study. Patients with KOA but additional OA in other joints (hip, hands) were excluded. The frequencies of hypertension, hyperglycemia/diabetes and obesity significantly higher in patients with KOA compared to the control group (Table). However, diabetes/hyperglycemia and/or dyslipemia rates were not different between groups. Metabolic syndrome was also significantly more prevalent among patients with KOA (Table). When analyzing the history of complications of cardiovascular disease such as ischemic heart disease or cerebrovascular complications, patients with KOA also showed a significantly higher rate as compared with the control group (16/184 (8.7%) vs. 9/254 (3.5%), p<0.05). [Table]
Conclusions In a primary care setting patients with knee OA showed a high frequency of cardiovascular risk factors and metabolic syndrome and what is more important cardiovascular disease complications appeared to be also more frequent in this population.
Disclosure of Interest None Declared
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