Article Text

PDF
FRI0436 Is gout still the rich and dissolute men’s disease? Results from the king study of the italian society for rheumatology (SIR)
  1. M. Manara1,
  2. C.A. Scirè1,
  3. M.A. Cimmino2,
  4. M. Govoni3,
  5. F. Salaffi4,
  6. M.C. Monti5,
  7. C. Montecucco6,
  8. M. Matucci-Cerinic7,
  9. G. Minisola8
  10. and co-authors of the KING Study Group
  1. 1Epidemiology Unit, Italian Society for Rheumatology, Milan
  2. 2University of Genoa, Genoa
  3. 3University of Ferrara, Ferrara
  4. 4University of Ancona, Jesi
  5. 5University of Pavia
  6. 6IRCCS San Matteo Foundation, Pavia
  7. 7University of Florence, Florence
  8. 8San Camillo Forlanini Hospital, Rome, Italy

Abstract

Background Gouty patients are commonly supposed to have unhealthy lifestyle habits. Recent studies have focused on the importance of the intervention on lifestyle factors for the prevention of gout in the spectrum of the metabolic syndrome [1].

Objectives To compare lifestyle habits of a random sample of patients with gout in rheumatologic setting to official data on general population of Italy.

Methods Data were extracted from the dataset of an ongoing multicentre cohort study including patients with prevalent clinically diagnosed gout (Kick-off of the Italian Network for Gout, KING, sponsored by SIR), recruited from June 2011 and January 2012 from 30 rheumatology practices across Italy. Socio-demographic data and lifestyle habits were systematically collected in order to measure indicators consistent with available national surveys. Last available national data were retrieved from the 2010 release of the Health for All [2], stratifying for the maximum level of detail in terms of gender, classes of age and region.

Analyzed variables included: employment status (employed vs. unemployed), educational level (high school degree), obesity (body mass index ≥30), smoking (current smokers), wine consumption (>0.5 l/day), beer consumption (usual drinker), beef meat, sausages, pork meat and fish intake (sometimes in a week), and vegetables intake (≥1 portion/day).

The relative increase of exposure in gouty patients was estimated by standardized prevalence ratios, taking into count gender, age and geographical distribution. Results are presented as standardized prevalence ratio [95% confidence intervals, CI].

Results The study population included 450 patients (M:F ratio of 9:1, mean (SD) age of 63.7 (11.6) years and median (IQR) disease duration of 3.4 (1.4-9.7) years).

Compared to general population, gouty patients showed a lower employment rate (0.46 [CI 0.43, 0.49]) and a lower prevalence of high school education (0.77 [CI 0.73, 0.80]), indicating lower socio-economic status. A higher prevalence of obesity (1.85 [CI 1.64, 2.06]), a lower prevalence of smoking (0.49 [CI 0.74, 0.94]) and a higher prevalence of wine (2.23 [CI 1.45, 3.01]) and beer (3.07 [CI 1.58, 4.55]) consumption was also observed. Further, gouty patients consumed less beef meat (0.78 [CI 0.75, 0.82]), more sausages (1.08 [CI 1.06, 1.10]), less pork meat (0.73 [CI 0.72, 0.75]), more vegetables (1.57 [CI 1.53, 1.61]) and a similar amount of fish (0.99 [CI 0.96, 1.03]) than Italian general population.

Conclusions Gout is clearly no longer associated with a higher socio-economic status, but gouty patients’ lifestyle is still far different from the recommended. Further efforts should be put in each level of prevention for lifestyle modification.

  1. Choi HK. A prescription for lifestyle change in patients with hyperuricemia and gout.Curr Opin Rheumatol. 2010;22:165-72.

  2. http://www.istat.it/it/archivio/14562

Disclosure of Interest None Declared

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.