THU0152 How should the primary endpoint be analysed in rheumatoid arthritis trials which mandate rescue prior to the clinical endpoint? Analysis of three phase 3 trials of tofacitinib

R. Fleischmann; D. Gruben; S. Krishnaswami; S.H. Zwillich; B. Benda; C.A. Mebus; J. Bradley

doi:10.1136/annrheumdis-2012-eular.2117

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Rheumatoid arthritis – non-biologic treatment and small molecules

THU0152 How should the primary endpoint be analysed in rheumatoid arthritis trials which mandate rescue prior to the clinical endpoint? Analysis of three phase 3 trials of tofacitinib

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Jan 2017	38	1	18
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Apr 2017	4	0	0
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Jun 2017	18	0	5
Jul 2017	16	0	1
Aug 2017	8	0	3
Sep 2017	20	0	2
Oct 2017	22	0	7
Nov 2017	20	0	5
Dec 2017	15	0	4
Jan 2018	32	0	4
Feb 2018	34	0	2
Mar 2018	26	0	1
Apr 2018	12	0	0
May 2018	14	0	0
Jun 2018	22	0	0
Jul 2018	28	0	1
Aug 2018	12	0	1
Sep 2018	8	0	0
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Jun 2022	2	0	0
Jul 2022	10	0	0
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Dec 2022	4	0	0
Jan 2023	20	0	0
Feb 2023	6	0	0
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Sep 2023	6	0	0
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Jan 2024	5	0	0
Feb 2024	2	0	0
Mar 2024	2	0	0
Total	958	3	94

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