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Advances in targeted therapies XIII
  1. FC Breedveld1,
  2. JR Kalden2,
  3. JS Smolen3
  1. 1Department of Rheumatology C4-r, University Hospital Leiden, Leiden, Netherlands
  2. 2Institute for Clinical Immunology and Rheumatology, Erlangen, Germany
  3. 3Department of Rheumatology, Medical University of Vienna, Vienna, Austria
  1. Correspondence to Professor FC Breedveld, Department of Rheumatology C4-r, University Hospital Leiden, Leiden 2300 RC, Netherlands; f.c.breedveld{at}

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The papers brought together in this supplement of the Annals of the Rheumatic Diseases constitute summaries of presentations at the XIIIth International Symposium on Advances in Targeted Therapies, which was held from 6 to 9 April 2011. These presentations represent the state of the art on the biology of mechanisms of action and pathophysiology of tumour necrosis factor (TNF) and other important mediators of inflammation. Current knowledge on the means and consequences of blocking TNF or other molecules or cellular mechanisms is also presented.

We are grateful to Drs Crofford, Feldmann, …

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