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Patients with arthralgia and auto-antibodies such as anticitrullinated protein antibodies and/or IgM-rheumatoid factor (seropositive) are at risk for developing rheumatoid arthritis (RA).1 RA is associated with lower alcohol intake, suggesting that alcohol consumption is protective for the development of RA.2,–,5 The proposed mechanism for this effect is that alcohol is immunosuppressive, possibly via intrinsic corticosteroid production. In animal …
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