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Clinical applicability of the EULAR Sjögren's syndrome disease activity index: a cumulative ESSDAI score adds in describing disease severity
  1. Anna P Risselada,
  2. Aike A Kruize,
  3. Johannes W J Bijlsma
  1. Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands
  1. Correspondence to Dr Anna P Risselada, Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Box 85500, 3508 GA, Utrecht, The Netherlands; a.p.risselada-2{at}umcutrecht.nl

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The European League Against Rheumatism (EULAR) Sjögren's task force proposed the EULAR Sjögren's syndrome disease activity index (ESSDAI) in 2010.1 This index scores the activity of primary Sjögren's syndrome (pSS) within 12 organ domains, intended for both clinical trials and daily practice. For the construction of the index, patients and vignettes with (highly) active systemic disease were used. No reports applying ESSDAI on a clinical cohort have been published yet. Our aim is to determine the applicability of ESSDAI as an activity index in clinical practice and we propose a cumulative ESSDAI score for describing disease severity.

We retrospectively analysed the medical charts of all patients with pSS according to the …

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