Efficacy of tocilizumab in patients with moderate to severe active rheumatoid arthritis and a previous inadequate response to disease-modifying antirheumatic drugs: the ROSE study

Yusuf Yazici; Jeffrey R Curtis; Akgun Ince; Herbert Baraf; Raymond L Malamet; Lichen L Teng; Arthur Kavanaugh

doi:10.1136/ard.2010.148700

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Clinical and epidemiological research

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Efficacy of tocilizumab in patients with moderate to severe active rheumatoid arthritis and a previous inadequate response to disease-modifying antirheumatic drugs: the ROSE study

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	Abstract	Full	Pdf
Sep 2011	248	24	97
Oct 2011	196	133	180
Nov 2011	70	74	98
Dec 2011	285	33	73
Jan 2012	1407	64	236
Feb 2012	519	35	101
Mar 2012	380	83	108
Apr 2012	254	47	62
May 2012	236	47	75
Jun 2012	199	39	56
Jul 2012	174	42	53
Aug 2012	74	34	43
Sep 2012	106	30	43
Oct 2012	158	35	64
Nov 2012	150	38	47
Dec 2012	147	22	46
Jan 2013	189	39	50
Feb 2013	103	55	46
Mar 2013	147	18	38
Apr 2013	130	21	36
May 2013	81	28	35
Jun 2013	77	19	36
Jul 2013	68	15	22
Aug 2013	65	14	19
Sep 2013	85	50	47
Oct 2013	94	81	64
Nov 2013	66	49	33
Dec 2013	60	32	22
Jan 2014	71	37	33
Feb 2014	55	34	36
Mar 2014	64	42	32
Apr 2014	101	44	45
May 2014	49	24	28
Jun 2014	23	29	24
Jul 2014	50	59	40
Aug 2014	33	37	38
Sep 2014	73	31	26
Oct 2014	55	42	28
Nov 2014	66	18	20
Dec 2014	45	36	28
Jan 2015	39	40	32
Feb 2015	44	23	29
Mar 2015	64	38	34
Apr 2015	47	27	38
May 2015	43	35	36
Jun 2015	52	24	25
Jul 2015	28	25	25
Aug 2015	22	25	21
Sep 2015	44	29	24
Oct 2015	34	21	19
Nov 2015	48	37	40
Dec 2015	41	33	18
Jan 2016	66	31	28
Feb 2016	39	30	27
Mar 2016	43	19	27
Apr 2016	107	23	27
May 2016	30	23	27
Jun 2016	39	25	27
Jul 2016	34	27	21
Aug 2016	30	15	13
Sep 2016	49	43	20
Oct 2016	37	59	40
Nov 2016	40	29	25
Dec 2016	42	24	20
Jan 2017	33	50	34
Feb 2017	15	39	25
Mar 2017	8	38	23
Apr 2017	11	45	40
May 2017	9	66	26
Jun 2017	18	64	34
Jul 2017	79	67	39
Aug 2017	74	54	43
Sep 2017	83	52	34
Oct 2017	68	56	32
Nov 2017	122	101	44
Dec 2017	214	191	26
Jan 2018	178	154	32
Feb 2018	141	113	34
Mar 2018	143	124	28
Apr 2018	105	91	15
May 2018	98	89	23
Jun 2018	87	73	16
Jul 2018	85	70	28
Aug 2018	90	84	22
Sep 2018	81	71	19
Oct 2018	85	83	25
Nov 2018	103	83	32
Dec 2018	80	74	11
Jan 2019	122	111	29
Feb 2019	72	60	28
Mar 2019	87	72	30
Apr 2019	46	39	21
May 2019	66	58	27
Jun 2019	52	52	23
Jul 2019	61	50	34
Aug 2019	73	66	18
Sep 2019	64	61	16
Oct 2019	61	55	20
Nov 2019	65	55	34
Dec 2019	73	67	24
Jan 2020	70	60	28
Feb 2020	69	63	39
Mar 2020	68	64	71
Apr 2020	58	54	81
May 2020	103	94	86
Jun 2020	83	78	58
Jul 2020	65	62	30
Aug 2020	62	54	22
Sep 2020	81	66	23
Oct 2020	106	98	35
Nov 2020	97	86	50
Dec 2020	81	71	37
Jan 2021	74	71	49
Feb 2021	59	55	31
Mar 2021	69	62	40
Apr 2021	121	116	53
May 2021	143	140	40
Jun 2021	62	51	30
Jul 2021	63	63	43
Aug 2021	63	60	33
Sep 2021	85	84	30
Oct 2021	85	72	35
Nov 2021	77	65	24
Dec 2021	76	74	21
Jan 2022	77	70	26
Feb 2022	57	45	18
Mar 2022	101	77	44
Apr 2022	91	86	31
May 2022	78	77	23
Jun 2022	80	75	13
Jul 2022	87	87	24
Aug 2022	88	79	14
Sep 2022	78	72	9
Oct 2022	63	63	15
Nov 2022	74	69	20
Dec 2022	72	66	22
Jan 2023	109	89	30
Feb 2023	121	110	23
Mar 2023	137	104	36
Apr 2023	84	77	26
May 2023	89	71	19
Jun 2023	80	70	22
Jul 2023	81	72	23
Aug 2023	99	87	31
Sep 2023	112	111	32
Oct 2023	152	140	47
Nov 2023	84	75	16
Dec 2023	142	111	27
Jan 2024	119	64	19
Feb 2024	111	100	24
Mar 2024	133	123	23
Total	14886	9050	5486

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