Table of contents

Clinical and epidemiological research

• Extended report: Clinical efficacy of leflunomide in primary Sjögren's syndrome is associated with regulation of T-cell activity and upregulation of IL-7 receptor α expression (6 May, 2012)

  Angela Bikker, Jan-Maarten van Woerkom, Aike A Kruize, Kim M G van der Wurff-Jacobs, Johannes W J Bijlsma, Floris P J G Lafeber, Joel A G van Roon
• Extended report: Patient's global assessment of disease activity and patient's assessment of general health for rheumatoid arthritis activity assessment: are they equivalent? (24 April, 2012)

  Nasim Ahmed Khan, Horace Jack Spencer, Essam Ahmed Abda, Rieke Alten, Christof Pohl, Codrina Ancuta, Massimiliano Cazzato, Pál Géher, Laure Gossec, Dan Henrohn, Merete Lund Hetland, Nevsun Inanc, Johannes WG Jacobs, Eduardo Kerzberg, Maria Majdan, Omondi Oyoo, Ruben A Peredo-Wende, Zahraa Ibrahim Selim, Fotini Nikolaos Skopouli, Alberto Sulli, Kim Hørslev-Petersen, Peter C Taylor, Tuulikki Sokka
• Extended report: Tocilizumab in patients with active rheumatoid arthritis and inadequate responses to DMARDs and/or TNF inhibitors: a large, open-label study close to clinical practice (21 May, 2012)

  Vivian P Bykerk, Andrew J K Östör, José Alvaro-Gracia, Karel Pavelka, José Andrés Román Ivorra, Winfried Graninger, William Bensen, Michael T Nurmohamed, Andreas Krause, Corrado Bernasconi, Andrea Stancati, Jean Sibilia
• Extended report: Influence of immunogenicity on the efficacy of longterm treatment of spondyloarthritis with infliximab (6 May, 2012)

  Chamaida Plasencia, Dora Pascual-Salcedo, Laura Nuño, Gema Bonilla, Alejandro Villalba, Diana Peiteado, Jesús Díez, Daniel Nagore, Ainhoa Ruiz del Agua, Rosario Moral, Emilio Martin-Mola, Alejandro Balsa
• Extended report:

  Clinical impact of MEFV mutations in children with periodic fever in a prevalent western European Caucasian population

  (12 May, 2012)

  Silvia Federici, Giuseppina Calcagno, Martina Finetti, Romina Gallizzi, Antonella Meini, Agata Vitale, Francesco Caroli, Marco Cattalini, Roberta Caorsi, Francesco Zulian, Alberto Tommasini, Antonella Insalaco, Maria Pia Sormani, Maurizia Baldi, Isabella Ceccherini, Alberto Martini, Marco Gattorno
• Extended Report: Prevalence and severity of interstitial lung disease in mixed connective tissue disease: a nationwide, cross-sectional study (1 May, 2012)

  Ragnar Gunnarsson, Trond Mogens Aaløkken, Øyvind Molberg, May Brit Lund, Georg Karl Mynarek, Åse Stavland Lexberg, Kari Time, Alvilde Sofie Strand Dhainaut, Liv-Turid Bertelsen, Øyvind Palm, Karen Irgens, Andrea Becker-Merok, Jan Leidulf Nordeide, Villy Johnsen, Sonja Pedersen, Anne Prøven, Lamya Samir Noori Garabet, Jan Tore Gran
• Extended report: Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome (5 May, 2012)

  Julia L Newton, James Frith, Danielle Powell, Kate Hackett, Katharine Wilton, Simon Bowman, Elizabeth Price, Colin Pease, Jacqueline Andrews, Paul Emery, John Hunter, Monica Gupta, Saravanan Vadivelu, Ian Giles, David Isenberg, Peter Lanyon, Adrian Jones, Marian Regan, Annie Cooper, Robert Moots, Nurhan Sutcliffe, Michele Bombardieri, Costantino Pitzalis, John McLaren, Steven Young-Min, Bhaskar Dasgupta, Bridget Griffiths, Dennis Lendrem, Sheryl Mitchell, Wan-Fai Ng
• Extended report: Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis (24 April, 2012)

  Gene-Siew Ngian, Joanne Sahhar, Susanna M Proudman, Wendy Stevens, Ian P Wicks, Sharon Van Doornum
• Extended report: Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients (1 June, 2012)

  Sebastien Viatte, Darren Plant, John Bowes, Mark Lunt, Stephen Eyre, Anne Barton, Jane Worthington
• Extended report: Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study (11 June, 2012)

  Joachim Gerss, Johannes Roth, Dirk Holzinger, Nicolino Ruperto, Helmut Wittkowski, Michael Frosch, Nico Wulffraat, Lucy Wedderburn, Valda Stanevicha, Dimitrina Mihaylova, Miroslav Harjacek, Claudio Len, Claudia Toppino, Massimo Masi, Kirsten Minden, Traudel Saurenmann, Yosef Uziel, Richard Vesely, Maria Teresa Apaz, Rolf-Michael Kuester, Maria Jesus Rua Elorduy, Ruben Burgos-Vargas, Maka Ioseliani, Silvia Magni-Manzoni, Erbil Unsal, Jordi Anton, Zsolt Balogh, Stefan Hagelberg, Henryka Mazur-Zielinska, Tsivia Tauber, Alberto Martini, Dirk Foell, for the Paediatric Rheumatology International Trials Organization (PRINTO)
• Concise report: The frequency of non-radiographic axial spondyloarthritis in relation to symptom duration in patients referred because of chronic back pain: results from the Berlin early spondyloarthritis clinic (21 August, 2012)

  Denis Poddubnyy, Henning Brandt, Janis Vahldiek, Inge Spiller, In-Ho Song, Martin Rudwaleit, Joachim Sieper
• Concise report: MRI inflammation and its relation with measures of clinical disease activity and different treatment responses in patients with ankylosing spondylitis treated with a tumour necrosis factor inhibitor (21 August, 2012)

  Pedro Machado, Robert B M Landewé, Jürgen Braun, Xenofon Baraliakos, Kay-Geert A Hermann, Benjamin Hsu, Daniel Baker, Désirée van der Heijde
• Concise report: Impact of tocilizumab therapy on antibody response to influenza vaccine in patients with rheumatoid arthritis (11 August, 2012)

  Shunsuke Mori, Yukitaka Ueki, Naoyuki Hirakata, Motohiro Oribe, Toshihiko Hidaka, Kazunori Oishi