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Autoantibodies
Toll-like receptor 9 (TLR9) controls B-cell differentiation in salivary glands (SG) of patients with Sjögren's syndrome (SS)
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  1. C Jamin,
  2. J-E Alard,
  3. J-O Pers,
  4. P Youinou
  1. EA 2216 « Immunologie et Pathologie » and IFR 148 ScInBioS, Université de Brest, and Université Européenne de Bretagne, Brest, France

https://doi.org/10.1136/ard.2010.129577q

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    Background

    Anti-EC antibodies (AECAs) may be pathogenic in vasculitides. Among a wide range of autoAg, they may recognise ATP synthase, a proton transport molecule regulating intracellular pH (pHi) expressed on the surface of ECs. The aim of the current study was to evaluate ATP synthase antigenicity in vasculitides, and anti-ATP …

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