Article Text
Other topics
Identification of cellular markers predicting relapses after immunoablation and autologous haematopoietic stem cell transplantation (ASCT) for refractory systemic lupus erythematosus
Statistics from Altmetric.com
Background
We recently showed that clinical remissions in systemic lupus erythematosus (SLE) after immunoablation and autologous haematopoietic stem cell transplantation (ASCT) are associated with depletion of the autoreactive immunological memory and the de novo generation of a juvenile and tolerant immune system. Nevertheless, relapses of SLE may occur.
Purpose
We further followed the clinical, serological and immunological data of our patients to identify predictive cellular markers for the development of lupus flares after ASCT.
Methods
Since 1998 …