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Footnotes
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Funding This work was supported by grants of the Netherlands Organisation for Scientific Research (NWO) (903-52-291, MDF, RRF, and Vici 918.56.602, MDF), and the Center of Medical System Biology (CMSB) within the framework of the Netherlands Genomics Initiative (NGI)/NWO.
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Competing interests None.
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Patient consent Not obtained. Detail has been removed from this case description to ensure anonymity. The editors and reviewers have seen the detailed information available and are satisfied that the information backs up the case the authors are making.
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Ethics approval This study was conducted with the approval of the local ethics committee of the Leiden University Medical Centre.
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Provenance and peer review Not commissioned; externally peer reviewed.