Article Text

PDF
High incidence of cardiovascular events in patients with rheumatoid arthritis
  1. K S S Steen1,
  2. W F Lems1,2,
  3. I M Visman2,
  4. M Heierman2,
  5. B A C Dijkmans1,2,
  6. J W R Twisk3,4,
  7. M Boers3,
  8. M T Nurmohamed1,2,5
  1. 1
    Department of Rheumatology, VU Medical Center, Amsterdam, The Netherlands
  2. 2
    Department of Rheumatology, Jan van Breemen Institute, Amsterdam, The Netherlands
  3. 3
    Department of Clinical Epidemiology and Biostatistics, VU Medical Center, Amsterdam, The Netherlands
  4. 4
    Institute of Health Sciences, VU Medical Center, Amsterdam, The Netherlands
  5. 5
    Department of Internal Medicine, VU Medical Center, Amsterdam, The Netherlands
  1. Correspondence to M T Nurmohamed, Department of Rheumatology, VU Medical Center, Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands; mt.nurmohamed{at}vumc.nl

Statistics from Altmetric.com

Rheumatoid arthritis (RA) is associated with higher risk for cardiovascular disease (CVD) in comparison with the general population.1 Traditional cardiovascular (CV) risk factors only partially explain the higher risk for CVD.2 There is increasing evidence that inflammation explains the enhanced CV risk in RA, as inflammation has a pivotal role in the development of atherosclerotic disease and this might be the link between increased atherosclerotic CVD and RA.3 Other RA-related factors might be undertreatment of CV comorbidity,1 and the use of non-steroidal anti-inflammatory drugs (NSAIDs) or selective cyclo-oxygenase 2 inhibitors.4,5

The objective of this prospective observational study was to determine the incidence of CV events in patients with RA in comparison to the general Dutch population, where the incidence of CV events is …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.