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Subluxing arthropathy: an unusual manifestation of the antisynthetase syndrome
  1. O Meyer1,
  2. H Charlanne2,
  3. P Cherin3,
  4. Y Allanore4,
  5. P Coquerelle5,
  6. B Grardel6,
  7. A-M Chamot7,
  8. E Hachulla2
  1. 1
    Department of Rheumatology, D. Diderot University, Bichat Teaching Hospital, AP-HP, Paris, France
  2. 2
    Department of Internal Medicine, Claude Huriez Teaching Hospital, Lille, France
  3. 3
    Department of Internal Medicine, Pitié-Salpêtrière Teaching Hospital, AP-HP, Paris, France
  4. 4
    Department of Rheumatology A, Paris Descartes University, Cochin Teaching Hospital, AP-HP, Paris, France
  5. 5
    Department of Rheumatology, Germon and Gauthier Hospital, Béthune, France
  6. 6
    Rheumatology Private Practice, Arras, France
  7. 7
    Rheumatology Private Practice, Morges, Switzerland
  1. Professor Olivier Meyer, Department of Rheumatology, CHU Bichat, 46 rue Henri Huchard, 75018 Paris France; olivier.meyer{at}bch.aphp.fr

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Antisynthetase syndrome was first described by Marguerie et al as a combination of polymyositis (or at least creatine kinase elevation), diffuse interstitial lung disease and autoantibodies to t-RNA synthetase.1

Joint signs and symptoms occur in up to 90% of patients with polymyositis or dermatomyositis2 and/or antisynthetase syndrome, occasionally as the initial manifestations. They include arthralgia, polyarthritis and deforming arthropathy with subluxation.

To establish a multicentre registry of patients with joint manifestations of antisynthetase syndrome, a standardised form was posted on the CRI (Club Rhumatismes et Inflammation) website (http://www.cri-net.com), which is part of the French Society for Rheumatology, with the partnership of the French Society of Internal Medicine.

During a …

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