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We report the clinical observation of interferon beta-1a effectiveness in the treatment of skin lesions in a patient affected by multiple sclerosis (MS) and systemic sclerosis (SSc),1 suggesting a common pathogenesis.
A 51-year-old woman was admitted to the department of neurology of the “Federico II” University with a 5-day history of muscle weakness and sensory disturbance in her right leg preceded by optic neuritis. Diagnosis of MS, according to the McDonald2 criteria was carried out; the Expanded Examination Rating Scale (EDSS)3 was 3.5.
A trial of intravenous methylprednisolone resulted in relief of the patient’s symptoms. The neurological status improved …