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Multiple sclerosis and systemic sclerosis: efficacy of interferon beta on skin lesions
  1. P B Carrieri1,
  2. M Petracca1,
  3. S Montella1,
  4. M Delfino2,
  5. C Sepe3,
  6. A Gattoni3
  1. 1
    Department of Neurological Sciences, “Federico II” University, Naples, Italy
  2. 2
    Department of Dermatology, “Federico II” University, Naples, Italy
  3. 3
    Department of Clinical Internal Medicine F Magrassi, Second University of Naples, Naples, Italy
  1. Professor P B Carrieri, Department of Neurological Sciences, Via Pansini 5, 80131 Napoli, Italy; pbcarrieri{at}libero.it

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We report the clinical observation of interferon beta-1a effectiveness in the treatment of skin lesions in a patient affected by multiple sclerosis (MS) and systemic sclerosis (SSc),1 suggesting a common pathogenesis.

A 51-year-old woman was admitted to the department of neurology of the “Federico II” University with a 5-day history of muscle weakness and sensory disturbance in her right leg preceded by optic neuritis. Diagnosis of MS, according to the McDonald2 criteria was carried out; the Expanded Examination Rating Scale (EDSS)3 was 3.5.

A trial of intravenous methylprednisolone resulted in relief of the patient’s symptoms. The neurological status improved …

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