Article Text

PDF
Visfatin (pre-B cell colony-enhancing factor) gene expression in patients with rheumatoid arthritis
  1. H Matsui,
  2. A Tsutsumi,
  3. M Sugihara,
  4. T Suzuki,
  5. K Iwanami,
  6. M Kohno,
  7. D Goto,
  8. I Matsumoto,
  9. S Ito,
  10. T Sumida
  1. Division of Clinical Immunology, Major of Advanced Biomedical Applications, Graduate School of Comprehensive Human Science, University of Tsukuba, Tsukuba, Japan
  1. A Tsutsumi, Division of Clinical Immunology, Major of Advanced Biomedical Applications, Graduate School of Comprehensive Human Science, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Ibaraki, Japan; atsutsum{at}md.tsukuba.ac.jp

Statistics from Altmetric.com

Visfatin, also known as pre-B cell colony enhancing factor, is a cytokine-like protein originally cloned from peripheral blood mononuclear cells (PBMC) as a factor that enhances differentiation of pre-B cells in synergy with interleukin 7 (IL-)7 and stem cell factor.1 Visfatin is mainly produced in visceral white adipose tissues, and shows an insulin-like effect by binding to insulin receptors.2 Generally, visfatin is regarded as an adipokine, and elevated levels of serum visfatin in patients with type 2 diabetes,3 and obesity,4 have been reported. Interestingly, in visceral adipose tissues, macrophages seem to be the major source …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.