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In addition to insulin resistance and obesity, hyperuricemia is strongly associated with metabolic syndrome using different definitions in Chinese populations: a population-based study (Taichung Community Health Study)
  1. W-Y Lin1,6,
  2. C-S Liu1,6,
  3. T-C Li2,9,11,
  4. T Lin1,5,6,
  5. W Chen4,7,12,
  6. C-C Chen3,10,
  7. C-I Li2,
  8. C-C Lin1,6,8,11
  1. 1
    Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan
  2. 2
    Medical Research, China Medical University Hospital, Taichung, Taiwan
  3. 3
    Division of Endocrinology and Metabolism, Department of Medicine, China Medical University Hospital, Taichung, Taiwan
  4. 4
    Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan
  5. 5
    Center of Preventive Medicine, China Medical University Hospital, Taichung, Taiwan
  6. 6
    Department of Family Medicine, China Medical University, Taichung, Taiwan
  7. 7
    Pediatric Medicine, College of Medicine, China Medical University, Taichung, Taiwan
  8. 8
    School and Graduate Institute of Health Care Administration, College of Public Health, China Medical University, Taichung, Taiwan
  9. 9
    Graduate Institute of Chinese Medicine Science, China Medical University, Taichung, Taiwan
  10. 10
    Department of Endocrinology and Metabolism, College of Chinese Medicine, China Medical University, Taichung, Taiwan
  11. 11
    Institute of Health Care Administration, College of Health Science, Asia University, Taichung, Taiwan
  12. 12
    China Medical University Beigang Hospital, Yunlin, Taiwan
  1. C-C Lin, Department of Family Medicine, China Medical University Hospital, 2 Yue-Der Road, Taichung, Taiwan 404; cclin{at}www.cmuh.org.tw

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Hyperuricemia and metabolic syndrome (MetS) have been shown to increase the risk of hypertension, type 2 diabetes mellitus, and cardiovascular disease (CVD) and increase the risk of total and CVD mortality.1 2 Insulin resistance (IR) and central obesity have been recognised as the common underlying mechanism.3 4 The association between hyperuricemia and MetS has been studied, but most of these studies focused on Caucasians.5 In this study, we examined this relationship using five different definitions (proposed by the World Health Organization (WHO), the National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATPIII), the modified NCEP-ATPIII, the International Diabetes Federation (IDF), and the American Heart Association/National Heart, Lung, and Blood Institute (AHA/NHLBI)) in Taiwan.6

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