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Life-table analysis of etanercept with or without methotrexate in patients with psoriatic arthritis
  1. A Spadaro,
  2. F Ceccarelli,
  3. R Scrivo,
  4. G Valesini
  1. Dipartimento di Clinica e Terapia Medica, Rheumatology Unit, Università di Roma, Rome, Italy
  1. Professor Antonio Spadaro, Dipartimento di Clinica e Terapia Medica, Rheumatology Unit, Sapienza, Università di Roma, Azienda Policlinico Umberto I, Viale del Policlinico 155, 00161 Rome, Italy; a.spadaro.reuma{at}virgilio.it

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The recent analysis of data included in the Stockholm TNFα Follow- Up (STURE) registry showed that the concomitant use of methotrexate (MTX) with etanercept (ETN), adalimumab or infliximab was associated with long-term drug survival of anti-tumour necrosis factor (TNF) agents in patients with psoriatic arthritis (PsA).1 The positive effect of MTX was primarily linked to fewer drop-outs due to adverse events.1 This analysis did not consider each anti-TNF drug subgroup. For this reason we determined the cumulative probability of taking ETN with or without MTX in a large cohort of patients.

We prospectively studied 82 patients, admitted to our rheumatological unit since 2001, affected by PsA, classified …

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