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Ann Rheum Dis 66:138-140 doi:10.1136/ard.2006.055541
  • Letter

Comparison of different outcome measures for psoriatic arthritis in patients treated with infliximab or placebo

  1. B Vander Cruyssen,
  2. F De Keyser,
  3. E Kruithof,
  4. H Mielants,
  5. F Van den Bosch
  1. Department of Rheumatology, Ghent University Hospital, Gent, Belgium
  1. Correspondence to:
    B Vander Cruyssen
    Department of Rheumatology, Ghent University Hospital, B-9000 Gent, Belgium; bert.vandercruyssen{at}ugent.be
  • Accepted 2 April 2006

Psoriatic arthritis (PsA) shares features with the spondyloarthropathy (SpA) concept and with rheumatoid arthritis. Treatment of PsA should target the skin, the SpA-like features and the rheumatoid arthritis-like features of the disease. Effects of treatment can be measured by one index covering different axes at once or by evaluating each axis separately.1 In this analysis, we evaluated different composite indices that have been validated in rheumatoid arthritis and compared them with the Psoriatic Arthritis Response Criteria (PsARC).2

The study population consisted of 18 patients with PsA, previously enrolled in a randomised monocentre double-blind placebo-controlled study evaluating effect of infliximab in patients with SpA,3 of whom nine received placebo. Patients were evaluated at baseline and at weeks 1, 2, 6, 8 and 12, which included the evaluation of the single components included in the PsARC, the Disease Activity Score using 28 joint counts (DAS28)4 and the DAS response (http://www.das-score.nl). A …