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Attenuated response to purified protein derivative in patients with rheumatoid arthritis
  1. S Nizam,
  2. P Emery
  1. Academic Unit of Musculoskeletal Disease, Second Floor, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK
  1. Correspondence to:
    Professor P Emery
    p.emery{at}leeds.ac.uk

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The article by Ponce de Leon et al1 highlights an important point that patients with rheumatoid arthritis (RA) have deficient cell mediated immunity. Therefore interpretation of delayed type hypersensitivity (DTH) is likely to be fraught with difficulties. This aspect of RA has been documented in a previous study,2 which examined the …

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