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- allogeneic haematopoietic stem cell transplantation
- autoimmune disease
- aplastic anaemia
Haematopoietic stem cell transplantation (HSCT) is a recent potential treatment for severe autoimmune disease (AID).1 Few reports of results in severe psoriasis have been published.2,3,4,5,6,7,8,9,10 We report lasting benefit for 20 years after allogeneic HSCT in a patient with disabling psoriatic arthropathy.
A 29 year old man was admitted to hospital in 1985 with petechia. Extensive psoriasis had developed at age 13. In 1984, severe polyarthritis developed with swelling and tenderness of fingers, toes, and right heel. Range of motion was markedly decreased in shoulders and one hip. The right sacroiliac (SI) joint was tender. Radiography showed sclerosis of SI joints and partial fusion on the left. A bone scan showed increased uptake in many …