Article Text

PDF
Amelioration of severe psoriasis with psoriatic arthritis for 20 years after allogeneic haematopoietic stem cell transplantation
  1. A C Woods,
  2. M J Mant
  1. Division of Hematology and Oncology, Department of Medicine, University of Alberta and University of Alberta Hospital, Edmonton, Alberta, Canada
  1. Correspondence to:
    Dr M J Mant
    2E3.32 Walter C Mackenzie Health Sciences Center, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2R7; Patty.Wark{at}ualberta.ca

Statistics from Altmetric.com

Haematopoietic stem cell transplantation (HSCT) is a recent potential treatment for severe autoimmune disease (AID).1 Few reports of results in severe psoriasis have been published.2,3,4,5,6,7,8,9,10 We report lasting benefit for 20 years after allogeneic HSCT in a patient with disabling psoriatic arthropathy.

A 29 year old man was admitted to hospital in 1985 with petechia. Extensive psoriasis had developed at age 13. In 1984, severe polyarthritis developed with swelling and tenderness of fingers, toes, and right heel. Range of motion was markedly decreased in shoulders and one hip. The right sacroiliac (SI) joint was tender. Radiography showed sclerosis of SI joints and partial fusion on the left. A bone scan showed increased uptake in many …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.