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Behçet’s disease with life-threatening haemoptoe and pulmonary aneurysms: complete remission after infliximab treatment
  1. K Baki1,
  2. P M Villiger2,
  3. D Jenni3,
  4. T Meyer3,
  5. J H Beer3
  1. 1Department of Medicine, Kantonsspital Baden, Baden, Switzerland
  2. 2Department of Rheumatology and Clinical Immunology/Allergology, University Hospital of Bern, Bern, Switzerland
  3. 3Department of Medicine, Kantonsspital Baden
  1. Correspondence to:
    P M Villiger
    Department of Rheumatology and Clinical Immunology/Allergology, University Hospital, CH 3010 Bern, Switzerland; peter.villiger{at}insel.ch

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A 25-year-old man was admitted to our hospital because of life-threatening haemoptoe and haematemesis. Recurring painful oral and genital aphtae and an episode of epididymitis led to a diagnosis of Behçet’s disease 18 months earlier.1 Treatment with colchicine (1 mg/day) and prednisone (50 mg/day) was started, with a rapid tapering of prednisone. Intermittent fever and a cardiac murmur led to the suspicion of endocarditis 6 months later. Transoesophageal echocardiography disclosed a right ventricular cardiac thrombus of 4 cm diameter. The clinical investigation did not show signs of vasculitis nor could a thrombophilia be diagnosed. Oral anticoagulation was initiated and continued until complete resolution of the cardiac thrombus. Azathioprine (75 mg/day) was prescribed in combination with prednisone (75 mg/day), with the recommendation …

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