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Ann Rheum Dis 2005;64:iv48-iv51 doi:10.1136/ard.2005.042572
  • Joint damage

Presentation and analysis of radiographic data in clinical trials and observational studies

  1. R Landewé,
  2. D van der Heijde
  1. University Hospital Maastricht, Department of Internal Medicine/Rheumatology, Maastricht, The Netherlands
  1. Correspondence to:
    R Landewé
    University Hospital Maastricht, Department of Internal Medicine/Rheumatology, PO Box 5800, 6202AZ Maastricht, the Netherlands; rlansint.azm.nl

    Abstract

    Despite the advent of sophisticated imaging systems, plain radiography continues to be a valuable outcome variable in clinical trials of inflammatory disorders for a number of reasons. This paper discusses the pros and cons of the different ways in which radiographic data in trials is presented; the minimum time needed to demonstrate radiographic progression in the context of a clinical trial; and the best ways to statistically analyse radiographic data.

    Footnotes

    • Competing interests: none declared

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