Article Text
Assessment: domains and instruments
Imaging the joint and enthesis: insights into pathogenesis of psoriatic arthritis
Abstract
The distinct radiographic features of psoriatic arthritis (PsA) help confirm it as a distinct entity from rheumatoid arthritis and highlight some unique non-synovial based disease imaging features. The advent of magnetic resonance imaging and a better understanding of joint microanatomy including the complexity of joint entheses provide a unifying anatomical and biomechanical concept that links disease at the apparently disparate sites of involvement in PsA, including the synovium, the enthesis, the bone and the periosteum. These findings suggest a reason for the localisation of disease to skeletal sites that are subject to repeated mechanical stressing.
- MRI, magnetic resonance imaging
- PsA, psoriatic arthritis
- RA, rheumatoid arthritis
- SpA, spondyloarthropathy
- enthesis
- magnetic resonance imaging
- pathogenesis
- psoriasis
- psoriatic arthritis
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Footnotes
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D McGonagle is funded by the Medical Research Council, UK