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Ann Rheum Dis 64:ii18-ii23 doi:10.1136/ard.2004.033217
  • Psoriatic arthritis and psoriasis: classification, clinical features, pathophysiology, immunology, genetics

Psoriasis: epidemiology, clinical features, and quality of life

  1. R G B Langley1,
  2. G G Krueger2,
  3. C E M Griffiths3
  1. 1Division of Dermatology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
  2. 2Department of Dermatology, University of Utah, Salt Lake City, Utah, USA
  3. 3Dermatology Centre, University of Manchester, Hope Hospital, Manchester, UK
  1. Correspondence to:
    Dr R G B Langley
    Division of Dermatology, Department of Medicine, Dalhousie University, 4195 Dickson Building, 5820 University Avenue, Halifax, Nova Scotia, Canada B3H 1V6; rgblangldal.ca

    Abstract

    Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. It can have a significant negative impact on the physical, emotional, and, psychosocial wellbeing of affected patients. Psoriasis is found worldwide but the prevalence varies among different ethnic groups. It has a strong genetic component but environmental factors such as infections can play an important role in the presentation of disease. There are several clinical cutaneous manifestations of psoriasis but most commonly the disease presents as chronic, symmetrical, erythematous, scaling papules and plaques. The epidemiology, clinical features, and impact on quality of life of psoriasis are reviewed.