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Positron emission tomography/computed tomography (PET/CT scan) represents a new molecular imaging modality using physiological tracers to assess a lesion’s metabolic state. [18F]Fluorodeoxyglucose (FDG) PET appears to be very good for the evaluation of cancer lesions and potentially useful in inflammatory rheumatic disorders, but there is scant information in ankylosing spondylitis (AS).
We evaluated an FDG-PET/CT scan (4 MBq/kg FDG injection, whole body acquisition using a Siemens Biograph Duo device, volumic fixation values are expressed as standardised uptake values (SUVs)), in patients with AS (revised New York criteria) with magnetic resonance imaging (MRI) documented lumbar aseptic spondylodiscitis (discovertebral biopsy in two patients) requiring anti-tumour necrosis factor (TNF) treatment. A second PET evaluation …