A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate

S B Cohen; L W Moreland; J J Cush; M W Greenwald; S Block; W J Shergy; P S Hanrahan; M M Kraishi; A Patel; G Sun; M B Bear

doi:10.1136/ard.2003.016014

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Extended reports

A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate

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	Abstract	Full	Pdf
Apr 2004	47	0	103
May 2004	71	0	116
Jun 2004	67	0	61
Jul 2004	56	0	28
Aug 2004	194	96	167
Sep 2004	133	183	125
Oct 2004	68	81	47
Nov 2004	54	65	44
Dec 2004	24	35	26
Jan 2005	36	58	38
Feb 2005	44	74	31
Mar 2005	34	47	25
Apr 2005	28	45	20
May 2005	40	58	27
Jun 2005	27	70	21
Jul 2005	23	33	24
Aug 2005	19	62	27
Sep 2005	13	32	48
Oct 2005	28	75	61
Nov 2005	24	44	46
Dec 2005	19	35	48
Jan 2006	16	34	20
Feb 2006	20	42	36
Mar 2006	14	46	38
Apr 2006	23	47	44
May 2006	18	32	31
Jun 2006	27	27	23
Jul 2006	8	37	23
Aug 2006	26	37	36
Sep 2006	28	35	38
Oct 2006	18	42	40
Nov 2006	11	47	33
Dec 2006	13	32	29
Jan 2007	19	36	42
Feb 2007	28	29	23
Mar 2007	30	35	30
Apr 2007	41	8	16
May 2007	29	30	20
Jun 2007	24	12	16
Jul 2007	22	21	22
Aug 2007	20	13	23
Sep 2007	25	14	18
Oct 2007	25	18	30
Nov 2007	22	10	20
Dec 2007	13	5	6
Jan 2008	34	7	11
Feb 2008	36	16	14
Mar 2008	20	12	14
Apr 2008	31	26	19
May 2008	55	16	16
Jun 2008	29	9	24
Jul 2008	41	5	10
Aug 2008	72	14	16
Sep 2008	46	14	16
Oct 2008	51	11	17
Nov 2008	36	5	12
Dec 2008	22	9	16
Jan 2009	29	13	22
Feb 2009	20	10	18
Mar 2009	51	16	24
Apr 2009	29	7	16
May 2009	20	7	18
Jun 2009	26	5	14
Jul 2009	31	5	13
Aug 2009	20	2	8
Sep 2009	26	5	12
Oct 2009	32	8	18
Nov 2009	25	5	10
Dec 2009	96	4	16
Jan 2010	23	2	9
Feb 2010	12	4	11
Mar 2010	23	9	11
Apr 2010	7	3	8
May 2010	16	9	18
Jun 2010	19	10	10
Jul 2010	13	8	14
Aug 2010	24	3	14
Sep 2010	8	5	5
Oct 2010	16	6	13
Nov 2010	18	5	8
Dec 2010	15	2	1
Jan 2011	12	6	7
Feb 2011	21	12	3
Mar 2011	21	9	16
Apr 2011	20	2	8
May 2011	24	12	10
Jun 2011	17	12	5
Jul 2011	23	3	5
Aug 2011	18	5	8
Sep 2011	19	4	5
Oct 2011	17	5	5
Nov 2011	17	5	4
Dec 2011	27	7	16
Jan 2012	26	15	15
Feb 2012	22	9	10
Mar 2012	28	10	20
Apr 2012	25	17	13
May 2012	18	12	14
Jun 2012	24	6	19
Jul 2012	40	15	24
Aug 2012	22	13	25
Sep 2012	18	7	12
Oct 2012	20	10	17
Nov 2012	37	15	22
Dec 2012	34	7	14
Jan 2013	53	13	15
Feb 2013	31	21	24
Mar 2013	61	23	25
Apr 2013	56	9	24
May 2013	35	13	13
Jun 2013	13	6	12
Jul 2013	13	6	12
Aug 2013	16	14	14
Sep 2013	34	15	13
Oct 2013	16	10	5
Nov 2013	67	35	11
Dec 2013	27	9	14
Jan 2014	16	12	8
Feb 2014	32	9	25
Mar 2014	27	16	34
Apr 2014	40	12	15
May 2014	44	13	24
Jun 2014	33	18	18
Jul 2014	23	24	10
Aug 2014	10	15	9
Sep 2014	28	18	17
Oct 2014	20	17	14
Nov 2014	15	16	16
Dec 2014	19	11	6
Jan 2015	20	23	20
Feb 2015	18	10	12
Mar 2015	13	13	9
Apr 2015	30	13	8
May 2015	23	11	15
Jun 2015	11	24	2
Jul 2015	14	11	12
Aug 2015	24	14	26
Sep 2015	42	14	13
Oct 2015	21	7	10
Nov 2015	28	14	10
Dec 2015	32	10	10
Jan 2016	54	24	15
Feb 2016	37	8	7
Mar 2016	22	19	15
Apr 2016	31	21	19
May 2016	29	10	9
Jun 2016	17	17	8
Jul 2016	19	16	11
Aug 2016	26	11	9
Sep 2016	76	16	14
Oct 2016	38	16	16
Nov 2016	19	18	17
Dec 2016	30	25	13
Jan 2017	34	33	19
Feb 2017	13	14	9
Mar 2017	7	27	8
Apr 2017	6	33	1
May 2017	3	34	5
Jun 2017	20	33	11
Jul 2017	51	45	21
Aug 2017	48	47	13
Sep 2017	62	38	14
Oct 2017	45	31	15
Nov 2017	54	42	11
Dec 2017	67	27	10
Jan 2018	35	25	6
Feb 2018	37	25	4
Mar 2018	48	37	17
Apr 2018	43	25	8
May 2018	43	36	5
Jun 2018	47	43	11
Jul 2018	40	34	6
Aug 2018	50	40	12
Sep 2018	73	63	9
Oct 2018	93	83	8
Nov 2018	74	72	3
Dec 2018	100	90	9
Jan 2019	80	76	16
Feb 2019	43	41	5
Mar 2019	55	47	17
Apr 2019	26	20	14
May 2019	25	20	13
Jun 2019	31	27	20
Jul 2019	39	27	15
Aug 2019	36	30	27
Sep 2019	20	18	8
Oct 2019	49	37	13
Nov 2019	38	35	13
Dec 2019	30	20	22
Jan 2020	34	30	6
Feb 2020	40	34	21
Mar 2020	27	27	17
Apr 2020	41	33	23
May 2020	44	34	15
Jun 2020	35	30	17
Jul 2020	30	24	13
Aug 2020	51	33	13
Sep 2020	53	41	15
Oct 2020	82	68	24
Nov 2020	40	26	10
Dec 2020	54	38	17
Jan 2021	26	18	8
Feb 2021	39	33	24
Mar 2021	81	63	20
Apr 2021	34	21	13
May 2021	79	75	16
Jun 2021	24	24	5
Jul 2021	25	25	26
Aug 2021	22	22	17
Sep 2021	34	34	22
Oct 2021	70	49	44
Nov 2021	59	34	37
Dec 2021	35	25	5
Jan 2022	35	27	9
Feb 2022	36	36	19
Mar 2022	42	40	8
Apr 2022	43	35	13
May 2022	51	47	37
Jun 2022	50	55	25
Jul 2022	29	28	5
Aug 2022	71	58	29
Sep 2022	84	67	44
Oct 2022	58	54	22
Nov 2022	79	73	19
Dec 2022	61	50	16
Jan 2023	69	65	11
Feb 2023	95	76	7
Mar 2023	66	56	10
Apr 2023	52	41	19
May 2023	52	42	18
Jun 2023	34	35	13
Jul 2023	42	38	12
Aug 2023	59	49	27
Sep 2023	68	54	21
Oct 2023	118	108	11
Nov 2023	244	212	15
Dec 2023	173	39	8
Jan 2024	145	17	20
Feb 2024	151	6	2
Mar 2024	475	17	5
Total	9700	6658	4552

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