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Ann Rheum Dis 63:321-323 doi:10.1136/ard.2003.008342
  • Concise report

Combined intravenous methotrexate and cyclophosphamide for refractory childhood lupus nephritis

Table 1

Results of treatment

Variable Before treatment After treatment Paired t test (p value)
Results are shown as mean (SD).
SLEDAI 13.8 (7.0) 4.4 (3.6) <0.01
Serum albumin (g/l) 28 (11) 41 (6) <0.025
Total protein (g/l) 52 (12) 67 (7) <0.025
C3 (g/l) 0.5 (0.1) 0.9 (0.4) <0.025
Serum creatinine (µmol/l) 100 (60) 80 (40) NS
Prednisone (mg/day) 27.6 (7.8) 12.5 (5.0) <0.01

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