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Inflammatory cytokines and rheumatoid corneal ulceration

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The ocular complications of rheumatoid arthritis include aqueous tear deficiency, scleritis, and central or paracentral corneal ulceration or perforation. The corneal ulcers are said to be non-inflammatory but ultrastructural changes have been found in the corneal stroma surrounding ulcers. Electron-dense deposits, thought possibly to indicate aggregated collagen, have been seen in the extracellular …

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