Cartilage turnover assessed with a newly developed assay measuring collagen type II degradation products: influence of age, sex, menopause, hormone replacement therapy, and body mass index

U Mouritzen; S Christgau; H-J Lehmann; L B Tankó; C Christiansen

doi:10.1136/ard.62.4.332

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Cartilage turnover assessed with a newly developed assay measuring collagen type II degradation products: influence of age, sex, menopause, hormone replacement therapy, and body mass index

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	Abstract	Full	Pdf
Mar 2003	59	73	54
Apr 2003	29	54	37
May 2003	6	40	14
Jun 2003	6	43	15
Jul 2003	17	57	5
Aug 2003	23	19	3
Sep 2003	17	30	9
Oct 2003	18	55	10
Nov 2003	35	29	8
Dec 2003	10	21	8
Jan 2004	15	34	11
Feb 2004	7	11	2
Mar 2004	19	24	11
Apr 2004	25	29	8
May 2004	40	44	4
Jun 2004	45	57	20
Jul 2004	40	74	22
Aug 2004	39	64	21
Sep 2004	22	60	12
Oct 2004	9	53	24
Nov 2004	7	45	21
Dec 2004	7	24	16
Jan 2005	17	39	15
Feb 2005	10	27	14
Mar 2005	18	42	23
Apr 2005	10	43	28
May 2005	4	28	25
Jun 2005	9	26	20
Jul 2005	9	36	27
Aug 2005	8	24	19
Sep 2005	15	23	26
Oct 2005	10	30	15
Nov 2005	14	31	30
Dec 2005	9	31	12
Jan 2006	9	25	11
Feb 2006	6	18	12
Mar 2006	9	19	23
Apr 2006	3	20	8
May 2006	7	16	12
Jun 2006	11	11	8
Jul 2006	7	22	17
Aug 2006	5	22	14
Sep 2006	8	15	22
Oct 2006	12	24	17
Nov 2006	7	21	11
Dec 2006	6	22	13
Jan 2007	12	46	27
Feb 2007	12	27	18
Mar 2007	14	20	19
Apr 2007	25	6	6
May 2007	14	4	3
Jun 2007	23	7	9
Jul 2007	6	6	10
Aug 2007	9	7	5
Sep 2007	9	11	4
Oct 2007	12	6	8
Nov 2007	15	3	5
Dec 2007	6	9	2
Jan 2008	11	1	6
Feb 2008	15	8	1
Mar 2008	17	0	0
Apr 2008	10	4	2
May 2008	19	5	2
Jun 2008	24	6	16
Jul 2008	23	2	2
Aug 2008	27	6	5
Sep 2008	18	4	0
Oct 2008	20	3	4
Nov 2008	16	3	3
Dec 2008	12	3	1
Jan 2009	16	4	2
Feb 2009	20	2	1
Mar 2009	22	5	9
Apr 2009	11	5	5
May 2009	14	8	3
Jun 2009	22	4	3
Jul 2009	8	4	2
Aug 2009	18	2	0
Sep 2009	14	3	2
Oct 2009	17	4	1
Nov 2009	19	5	2
Dec 2009	12	0	8
Jan 2010	10	2	3
Feb 2010	16	0	1
Mar 2010	18	11	4
Apr 2010	11	8	5
May 2010	6	2	1
Jun 2010	17	3	2
Jul 2010	6	0	3
Aug 2010	0	1	2
Sep 2010	10	4	8
Oct 2010	21	4	1
Nov 2010	12	1	0
Dec 2010	14	1	0
Jan 2011	13	1	0
Feb 2011	19	1	2
Mar 2011	19	4	1
Apr 2011	10	0	0
May 2011	19	3	3
Jun 2011	18	3	1
Jul 2011	19	3	1
Aug 2011	13	5	3
Sep 2011	15	1	1
Oct 2011	25	12	1
Nov 2011	21	9	4
Dec 2011	12	9	8
Jan 2012	12	12	7
Feb 2012	18	6	3
Mar 2012	5	10	2
Apr 2012	17	10	7
May 2012	7	10	10
Jun 2012	14	11	17
Jul 2012	17	15	18
Aug 2012	26	21	26
Sep 2012	34	17	25
Oct 2012	29	18	20
Nov 2012	33	19	11
Dec 2012	25	18	10
Jan 2013	31	24	20
Feb 2013	24	14	12
Mar 2013	37	31	5
Apr 2013	21	30	4
May 2013	34	14	9
Jun 2013	22	19	8
Jul 2013	24	12	11
Aug 2013	16	9	5
Sep 2013	20	15	9
Oct 2013	27	10	6
Nov 2013	28	16	13
Dec 2013	14	7	12
Jan 2014	21	7	7
Feb 2014	22	9	13
Mar 2014	23	14	26
Apr 2014	32	14	13
May 2014	20	12	2
Jun 2014	18	6	5
Jul 2014	26	9	5
Aug 2014	25	12	9
Sep 2014	17	7	6
Oct 2014	16	13	12
Nov 2014	20	11	3
Dec 2014	17	7	4
Jan 2015	21	12	5
Feb 2015	14	3	6
Mar 2015	15	5	4
Apr 2015	18	8	10
May 2015	14	2	10
Jun 2015	557	7	3
Jul 2015	410	5	3
Aug 2015	490	5	2
Sep 2015	579	22	6
Oct 2015	577	7	1
Nov 2015	574	6	5
Dec 2015	34	16	7
Jan 2016	28	8	3
Feb 2016	15	6	1
Mar 2016	20	11	8
Apr 2016	18	18	6
May 2016	14	8	12
Jun 2016	6	7	8
Jul 2016	7	7	8
Aug 2016	17	11	3
Sep 2016	24	5	7
Oct 2016	22	9	3
Nov 2016	70	9	12
Dec 2016	58	10	5
Jan 2017	63	8	3
Feb 2017	17	15	4
Mar 2017	8	38	9
Apr 2017	7	39	6
May 2017	5	27	3
Jun 2017	14	17	2
Jul 2017	32	28	6
Aug 2017	26	18	5
Sep 2017	32	20	4
Oct 2017	27	27	1
Nov 2017	36	34	3
Dec 2017	31	19	3
Jan 2018	46	36	5
Feb 2018	28	20	6
Mar 2018	26	12	7
Apr 2018	47	27	14
May 2018	26	20	8
Jun 2018	36	34	9
Jul 2018	32	28	5
Aug 2018	28	24	7
Sep 2018	29	25	6
Oct 2018	39	29	7
Nov 2018	25	19	3
Dec 2018	27	15	9
Jan 2019	28	9	14
Feb 2019	23	19	10
Mar 2019	27	15	13
Apr 2019	17	15	9
May 2019	24	7	17
Jun 2019	21	13	27
Jul 2019	15	11	6
Aug 2019	23	13	9
Sep 2019	11	9	6
Oct 2019	13	12	7
Nov 2019	8	4	4
Dec 2019	17	9	3
Jan 2020	21	17	6
Feb 2020	16	8	2
Mar 2020	10	6	7
Apr 2020	11	9	5
May 2020	17	13	6
Jun 2020	19	15	13
Jul 2020	16	12	12
Aug 2020	24	20	13
Sep 2020	30	25	6
Oct 2020	27	24	17
Nov 2020	20	12	13
Dec 2020	34	27	9
Jan 2021	24	12	13
Feb 2021	25	15	12
Mar 2021	19	11	4
Apr 2021	18	16	24
May 2021	15	11	12
Jun 2021	16	16	16
Jul 2021	16	16	7
Aug 2021	12	12	10
Sep 2021	32	32	40
Oct 2021	43	33	26
Nov 2021	29	21	21
Dec 2021	29	23	9
Jan 2022	20	15	7
Feb 2022	43	25	10
Mar 2022	40	34	10
Apr 2022	60	42	11
May 2022	43	33	13
Jun 2022	37	31	8
Jul 2022	25	21	4
Aug 2022	42	35	10
Sep 2022	49	29	12
Oct 2022	35	31	10
Nov 2022	35	27	3
Dec 2022	34	30	5
Jan 2023	43	40	21
Feb 2023	46	47	10
Mar 2023	54	40	9
Apr 2023	19	7	10
May 2023	11	9	7
Jun 2023	31	27	11
Jul 2023	23	13	9
Aug 2023	26	22	12
Sep 2023	33	27	10
Oct 2023	27	27	9
Nov 2023	64	40	8
Dec 2023	85	13	3
Jan 2024	67	3	2
Feb 2024	61	3	1
Mar 2024	42	6	0
Total	8550	4380	2309

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