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Clinical comparisons of RA between different populations: are they feasible?
  1. J Cadena1,
  2. J-M Anaya2
  1. 1Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia
  2. 2School of Medicine, Universidad Pontificia Bolivariana, Medellín, Colombia
  1. Correspondence to:
    Dr J-M Anaya, Unidad de Reumatología CIB, Cra. 72-A No 78-B-141, Medellín, Colombia;
    jmanayacib.org.co

https://doi.org/10.1136/ard.62.11.1124-a

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    Rheumatoid arthritis (RA) is the most common chronic inflammatory disease, affecting about 1% of the white population, particularly female patients, and has considerable physical, psychological, and social repercussions.1

    In a paper published previously in the Annals, Dadoniene et al described and compared two cohorts of patients with RA from Vilnius (Lithuania) and Oslo (Norway).2 There were no significant differences in sex, age, extra-articular manifestations, education, or family history of RA between the groups. None the less, there were important differences in disease activity, disability, pain, emotional, mental and general health, with patients in the Vilnius group having the worst scores. The number of patients who had never used a disease modifying antirheumatic drug (DMARD) was similar in both groups. Vilnius patients had more commonly used azathioprine, sulfasalazine, and antimalarial drugs, whereas Oslo patients had used methotrexate, gold salts, cyclosporin, and d-penicillamine. Surgery was more common in the Oslo patients. That study …

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