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Behçet's disease and thrombophilia
  1. G E Ehrlich1
  1. 1University of Pennsylvania, Philadelphia, USA; g2e{at}mindspring.com
    1. M Leiba2,
    2. Y Sidi2,
    3. H Gur2,
    4. A Leiba2,
    5. M Ehrenfeld2
    1. 2Department of Medicine C and the Rheumatic Disease Unit, Sheba Medical Centre, Tel Hashomer and Sackler Faculty of Medicine, Tel Aviv University Faculty of Medicine, Tel Aviv, Israel

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      Surely the authors of the comprehensive review of Behçet's disease and thrombophilia1 meant to cite the year 1937, not 1973, for Behçet's eponymic description of the disease. However, contrary to their statement, Behçet was not the first to describe the disorder that now bears his name. He was preceded by Shigeta in Japan (1924), Amantiades in Greece (1931), and Whitewell in Great Britain (1934), probably also by Kurosawa, Lipschutz, and arguably even earlier by Hippocrates, among extant descriptions. Behçet deserves to have the disease named after him, however, because he was the first modern author to group the various ophthalmic, dermatological, and orogenital lesions together as a syndrome.

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      Authors' reply

      The authors thank Dr. Ehrlich for his comments. Obviously an overlooked typing error led to the wrong year of Hûlusi Behçet's first description in 1937, of the triad of recurrent oral aphthous ulcers, genital ulcers and uveitis as a single disease entity.

      Because other reports cited by Dr Ehrlich, as well as a few others, were reports which did not group all the findings into one disease, we did not relate to them. These include Hippocrates as the first to describe fever, aphthous ulcerations, genital ulcerations, chronic eye ailment, loss of vision, carbuncles etc,1 followed by Neumann in 1895,2 Blüthe in 1908,3 Planner and Remenowsky in 1922,4 Gilbert in 1925,5 Adamantiades in 1931,6 Dascalopoulos in 1932,7 and Whitwell in 1934.8

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