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Dust exposure: a missed environmental factor of Wegener's granulomatosis

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Infectious agents, genetic background, and environmental exposure as observed in this case report, are thought to play a part in Wegener's granulomatosis (WG).1


A 54 year old man consulted in 1999 for an eight year history of bilateral crusty and bloody rhinosinusitis. He had worked from 1965 to 1980 as a ship's carpenter. During this period he had constantly had nose pain, sore mucosal discomfort, frequent nasal bloody discharge, and chronic nasal obstruction when planing woods (iroko, oak, and ash), removing paint, and undertaking activities with dust exposure. He did not wear a mask. He had been a heavy smoker until the age of 40 and had never used cocaine. No nasal deformity was noted. Nasal fibroscopy disclosed erythematous and inflamed mucosa of the nasal …

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