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Letter
Osteocalcin: a marker of disease activity in ankylosing spondylitis?
  1. A Falkenbach1,
  2. M Herold2
  1. 1Gasteiner Heilstollen Hospital and Research Institute Gastein, A-5645 Bad Gastein, Austria
  2. 2University Hospital, Innsbruck Austria
  1. Correspondence to:
    Dr Falkenbach

https://doi.org/10.1136/ard.61.1.92

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    In rheumatic diseases the synovial concentration of osteocalcin, which represents osteoblast activity, is inversely correlated with the extent of joint inflammation.1 Synovial and serum osteocalcin correlate positively.1 In ankylosing spondylitis (AS) the serum concentration of osteocalcin has been reported to be low2,3 or normal.4–7 Cross sectional studies have shown no significant correlation between osteocalcin serum concentration and erythrocyte sedimentation rate (ESR) or C reactive protein.5,7

    To answer the question whether serum osteocalcin is a useful marker …

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