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Concise report
Rheumatological complications associated with the use of indinavir and other protease inhibitors
  1. E Florence,
  2. W Schrooten,
  3. K Verdonck,
  4. C Dreezen,
  5. R Colebunders*
  1. 1Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
  1. Correspondence to:
    Professor Colebunders, Department of Clinical Research, Institute of Tropical Medicine, Nationalestraat, 155, B-1000 Antwerp, Belgium;
    bcoleb{at}itg.be

Abstract

Several cases are reported of rheumatological pathology (temporomandibular dysfunction, frozen shoulder, Dupuytren's disease, and tendinitis) most probably related to the intake of indinavir in HIV positive patients. A survey using an anonymous questionnaire of 878 people with HIV infection treated with antiretroviral drugs suggests that other protease inhibitors may also cause arthralgia.

  • arthritis
  • frozen shoulder
  • HIV infection
  • protease inhibitor indinavir

https://doi.org/10.1136/ard.61.1.82

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    Footnotes

    • ↵* Also Department of Infectious and Tropical Diseases, University Hospital, Antwerp, Belgium