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AB0102 Antiphospholipid syndrome (aps) in children
  1. ME Pombo1,
  2. R Merino2,
  3. D Pascual3,
  4. MV Cuesta4,
  5. A Aguado5,
  6. J García-Consuegra2
  1. 1Rheumatology Service
  2. 2Pediatric Rheumatology Unit
  3. 3Inmunology Service
  4. 4Hematology Service
  5. 5Internal Medicine Service, Hospital Universitario La Paz, Madrid, Spain

Abstract

Objectives To evaluate clinical features and management options of persistent antiphospholipid antibodies (aPL) in children.

Methods Retrospective chart review of patients, seen between 1987 and 2000.

Results Six patients with ages at diagnosis ranging from 9 to 13 years are presented. One of them with primary APS and 3 with SLE and asymptomatic aPL. The clinical manifestations are shown in the Table 1. All of the patients included were positive for lupus anticoagulant and all of them except the case 4 had positive tests for aCL and Aβ2GPI.

Abstract AB0102 Table 1

Clinical manifestations and treatment

Conclusion In paediatric patients with aPL, the risk of thrombosis, their recurrences and the management of oral anticoagulation may be different from adults.

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