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THU0133 New approaches in diagnosis of sensor polyneuropathy in rheumatoid arthritis
  1. BF Nemtsov,
  2. LA Smirnova,
  3. OV Simonova
  1. Internal Medicine, Kirov State Medical Academy, Kirov, Russia

Abstract

Background Investigation of vibration perception disorders is a required method for diagnosis of sensor polyneuropathy (SPNP) in case of diabetes mellitus. SPNP is one of the most frequent extraarticular symptoms of rheumatoid arthritis (RA).

Objectives To develop and introduce a new express diagnostic method for SPNP in RA into clinical practice.

Methods 91 RA patients were studied. Of them, 91% were females and 9% were males. The majority of patients had a severe form of RA. 49% had extraarticular symptoms. SPNP was studied by means of measuring of vibration perception. The biothesiometer of the EG-Electronic Company was used. Lower extremities were investigated. In addition to that electroneuromyography (ENMG) was performed.

Results In more severe forms of RA the vibration perception considerably increased (p < 0.01). In the patients with extraarticular symptoms the above disorder was more severe and more frequent as compared with the patients who had no extraarticular symptoms (p < 0.0001). Comparison of the two diagnostic methods showed that ENMG and biothesiometry enable to diagnose SPNP with the same frequency (80% and 77% relatively).

Conclusion Thus, investigation of vibration perception is as effective as the routine ENMG. This is a painless fast express method. This new method enables to diagnose extraarticular symptoms in RA very quickly. It can be used as an additional evaluation criterion of RA severity.

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