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THU0126 Dexterity and anxiety in large cohort of rheumatoid arthritis patients
  1. SJ Stropuviene,
  2. J Jankauskiene,
  3. J Dadoniene,
  4. A Venalis
  1. Department of Rheumatology, Institute of Experimental and Clinical Medicine, Vilnius, Lithuania

Abstract

Background Psychological distress is often a leading condition in rheumatoid arthritis clinical picture in addition to disability and disease activity measures. Being long lasting process it makes an impact on disease coping process and management itself.1

Objectives The aim of the study was to determine which demographic and clinical variables relate to anxiety and depression most of all in 225 rheumatoid arthritis (RA) patients cohort.

Methods The study was performed as satellite project to Vilnius rheumatoid arthritis register. The patients were invited to participate in the study and to answer the questions concerning education and employment, physical phunctioning: ACR functional classes, dependence on relatives and HAQ and patients global assessment of health status. The disease activity was measured by physicians global assessment, pain VAS, morning stiffness and modified DAS. Anxiety and depression were measured by AIMS2 questioner particularly asking about mood alterations with range of possible answers: 1-never and 6-almost ever. The level 6,0 for anxiety and 4,0 for dexterity were used as cut of levels.2 The chi-square method was used for evaluation of associations and was qualified as significant if p < 0,05.

Results In this particular cohort we found that 32% of patients were experiencing the anxiety and even 42,2% – depressive moods. As the result, we found strong associations between anxiety levels with disease outcome measures: physical functioning classes (chi2 = 12,72; p = 0,00), disability indices (chi2 = 21,09; p = 0,00) and employment holding (chi2 = 5,62; p = 0,01). Global evaluation of disease activity by physician was the only one significantly correlated disease activity measure (chi2 = 12,51; p = 0,00). Dexterity levels showed the same significant associations with the same measures. In addition to it dexterity had one more additional significant association: the dependence on relatives made those patients evidently depressed (chi2 = 12,96; p = 0,00) but not anxious.

Conclusion The anxiety and depression status of 225 Ra patients turned out to be multidependent variables in strong association with social status, disability indices and ACR classes but physicians global assessment as the only one disease activity measure.

References

  1. Meenan RF, Gertman PM, Mason JH, Dunaif R. The arthritis impact measures scales. Arthritis Rheum. 1982;25:1048–53

  2. Hawley DJ, Wolfe F. Anxiety and depression in patients with rheumatoid arthritis: a prospective study of 400 patients. J Rheumatol. 1988;15:932–41

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